Macrocyclics

Macrocyclics 专业致力于生产用于核医学和医学成像的定制的螯合剂。我们为客户定制用于临床试验并且符合 cGMP（动态药品生产管理规范）标准的产品，我们提供生物偶联服务和咨询服务以便帮助客户选择适合其特定需求的同位素。

MACROCYCLICS 简介

从1995年开始 Macrocyclics 就成为了为医学提供高性能螯合剂技术的全球领导者。Macrocyclics 的团队致力于为客户提供发展成熟和富有创新的螯合剂与服务，帮助应对分子成像和核医学方面的挑战。

AREVA MED 简介

AREVA Med 是阿海珐 (AREVA) 下属公司，专门从事富有创新精神的抗癌治疗产品的开发。AREVA Med 为生产高纯度铅-212 (²¹²Pb) 开发了新工艺，这种稀有金属目前在发展前景良好的核医学研究领域处于核心地位。2011年，AREVA Med 收购了全球高性能螯合剂技术领导者 Macrocyclics。AREVA Med 还和美国国家癌症研究所 (NCI)、阿拉巴马大学伯明翰分校 (UAB) 及法国国家健康与医学研究院 (Inserm) 等世界级科学合作伙伴开展合作。2012年，AREVA Med 和罗氏 (Roche) 达成了战略联盟，以便共同创造全新、先进的阿尔法放射免疫治疗技术来锁定和消灭某些侵袭性特别强的癌症细胞。

Macrocyclics 产品列表：

Macrocyclics 双功能配体

p-SCN-Bn-TCMC

p-NO2-Bn-Cyclen

p-NO2-Bn-DOTA

p-NH2-Bn-DOTA

p-NH2-Bn-DOTA-tetra(t-Bu-ester)

p-SCN-Bn-DOTA

DOTA-tris (t-Bu ester)

DOTA-mono-NHS-tris(t-Bu ester)

Maleimido-mono-amide-DOTA-tris (t-Bu ester)

Maleimido-mono-amide-DOTA B-272

Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)

2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester)

Azido-mono-amide-DOTA-tris(t-butyl ester)

DOTA-NHS-ester

Azido-mono-amide-DOTA

p-NH2-Bn-DTPA

p-NH2-Bn-DTPA-penta (t-Bu ester)

p-SCN-Bn-DTPA

p-NH2-CHX-A\"-DTPA

CHX-A-DTPA

DTPA-tetra (t-Bu ester)

Maleimido-mono-amide-DTPA

p-NH2-Bn-PCTA

p-SCN-Bn-PCTA

p-NH2-Bn-oxo-DO3A

p-SCN-Bn-oxo-DO3A

p-NH2-Bn-NOTA

p-SCN-Bn-NOTA

Deferoxamine-p-SCN

Deferoxamine-maleimide

DOTA-Biotin-Sarcosine

Samplet Pack- Bifunctionals

Macrocyclics 大环配体

Cyclam

DO2A

DOTA

DOTP

DOTMA

TETA

DOTAM

DiAmSar

CB-Cyclam

CB-TE2A

NOTA

TACN

Macrocyclics 造影剂

Tm-DOTA

Gd-DOTA

Tm[DOTP]5-

Tm-DOTMA

Eu-DOTA-4AmC

Macrocyclics 中间体

BisCBZ-Cyclen

TrisBOC-Cyclen

DO2A-t-Bu-ester

DO3A-t-Bu-ester

• Bifunctional Chelators (BFCs)
• Conjugates
• Fluorescent Probes
• Macrocyclic Ligands
• Magnetic Resonance Reagents
• Reactive Intermediates

About the company Macrocyclics

Macrocyclics, Inc., a manufacturer of customized chelating agents, is dedicated to leading-edge development of new chelation chemistry platforms critical for advancement of diagnostic and therapeutic medicine.

Macrocyclics offers a large number of services in different areas.

Macrocyclics is operating in a brand new facility equipped with state of the art chemistry and biological laboratories as well as a radio-chemistry lab licensed to include all of the most popular radionuclides for PET imaging and therapeutic applications.

Our new facility was designed to expand our cGMP custom synthesis and bioconjugations services. New and improved capabilities include peptide synthesis, a dedicated radio-isotope hot-lab and two new analytical laboratories with UPLC, QTOF, CE, FTIR, polarimeter.